Cut three strand of wire measuring approx. 9", 10.5" and 13". Thread each thread through three of the comb holes (see image) and secure with crimp beads. 

To the shortest wire, thread on your 6mm and 8mm pearl beads and 3mm bicones in alternating order or your desired order. 
When you have threaded approx. 23 pearl beads on or the wire is almost full, secure the end to the other comb like in step 1 and secure with a crimp bead.

To the middle wire, thread on your 6mm and 8mm pearl beads and 3mm bicones in alternating order or your desired order. 
When you have threaded approx. 28 pearl beads on or the wire is almost full, secure the end to the other comb like in step 1 and secure with a crimp bead.

To the longest wire, thread on your 4mm pearl beads and a 3mm bicone after every 8 pearl beads. 
When you have threaded approx. 80 pearl beads (10 groups of 8 pearls)  on or the wire is almost full, secure the end to the other comb like in step 1 and secure with a crimp bead.

Add more bicones for extra sparkle!